Canadian scientists working on melt-in-the-mouth vaccine patches

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A team of scientists from McMaster University in Hamilton, Canada, is carrying out a new study that will allow vaccines and drugs to be taken into the body with melting tapes when they are attached to the mouth.

A team of scientists from McMaster University in Hamilton, Canada, is carrying out a new study that will allow vaccines and drugs to be taken into the body with melting tapes when they are attached to the mouth.

featured on CBC newsat McMaster University Chemistry and Chemical Professor of Biology. It was noted that the scientific team led by Alex Adronov was working with a biotechnology company on the ingestion of vaccines via thin strips that melt in the mouth.

NewsExplaining his views, Prof. Noting that many people do not like to be injected, Adronov said, “Therefore, there is an obvious advantage to the oral vaccine. So what we are trying to do is to give the vaccine components an oral and rapidly soluble injection, rather than an injection into the arm. film We want to try giving it with him.”

Positive results were obtained in the first trials on animals.

Stating that they are in the early discovery phase of the study, Adronov stated that they have seen that they can produce protein-loaded strips.

“Our team has completed the first animal study that showed positive results that animals were able to develop antibodies against the model protein that we delivered in this way. We now have a second animal where we will insert the Covid-19 spike protein into these strips to see if we can elicit an immune response against this spike protein,” Adronov said. We’re working on the study tour.” used the phrases.

Mark Upsdell, CEO of the Canadian biotechnology company involved in the research, also reminded that vaccines such as Pfizer and Moderna, which are still used in the fight against the Kovid-19 epidemic, should always remain in the cold chain between 15 and 80 degrees Celsius below zero.

“It will be possible to send vaccines even with an envelope”

Stating that this means the need for a complex freezer supply chain and temperature-controlled shipping methods, Mark Upsdell said:

“Our team was able to stabilize the proteins at 40 degrees Celsius. That changes the rules of the game. This is an important breakthrough. 60 percent or more of the countries in the world are in the hot zone. Considering all these countries that don’t have the logistics we have in North America, vaccines don’t need cold chain “It becomes even more important to transport these vaccines with these strips. It will be possible to send these vaccines to countries without infrastructure at a lower cost, even in an envelope. Transport costs will also come down a lot, a lot.”

When the research, which is carried out with the support of the Canadian National Research Council (NRC) and the Canadian Natural Sciences and Engineering Research Council (NSERC), is completed, some drugs and vaccines will be taken with mouth-melting patches.

Source: Anadolu Agency / Seyit Aydogan


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